Insulin-like Growth Factor 1 Signaling Axis Meets p53 Genome Protection Pathways
Clinical, epidemiological, and experimental evidence indicate that the insulin-like growth factors (IGFs) are important mediators in the biochemical chain of events that lead from a phenotypically normal to a neoplastic cell. The IGF1 receptor (IGF1R), which mediates the biological actions of IGF1 a...
Main Authors: | , , , |
---|---|
Format: | Online |
Language: | English |
Published: |
Frontiers Media S.A.
2016
|
Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4917523/ |