Utility of Lymphoblastoid Cell Lines for Induced Pluripotent Stem Cell Generation

A large number of EBV immortalized LCLs have been generated and maintained in genetic/epidemiological studies as a perpetual source of DNA and as a surrogate in vitro cell model. Recent successes in reprograming LCLs into iPSCs have paved the way for generating more relevant in vitro disease models...

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Bibliographic Details
Main Authors: Kumar, Satish, Curran, Joanne E., Glahn, David C., Blangero, John
Format: Online
Language:English
Published: Hindawi Publishing Corporation 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4914736/