SREBP-2 promotes stem cell-like properties and metastasis by transcriptional activation of c-Myc in prostate cancer

SREBP-2 promotes stem cell-like properties and metastasis by transcriptional activation of c-Myc in prostate cancer

Sterol regulatory element-binding protein-2 (SREBP-2) transcription factor mainly controls cholesterol biosynthesis and homeostasis in normal cells. The role of SREBP-2 in lethal prostate cancer (PCa) progression remains to be elucidated. Here, we showed that expression of SREBP-2 was elevated in ad...

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Bibliographic Details
Main Authors: Li, Xiangyan, Wu, Jason Boyang, Li, Qinlong, Shigemura, Katsumi, Chung, Leland W.K., Huang, Wen-Chin
Format: Online
Language:English
Published: Impact Journals LLC 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4914327/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4914327/

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