Accelerated geroncogenesis in hereditary breast-ovarian cancer syndrome

Accelerated geroncogenesis in hereditary breast-ovarian cancer syndrome

The geroncogenesis hypothesis postulates that the decline in metabolic cellular health that occurs naturally with aging drives a “field effect” predisposing normal tissues for cancer development. We propose that mutations in the cancer susceptibility genes BRCA1/2 might trigger “accelerated geroncog...

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Bibliographic Details
Main Authors:	Menendez, Javier A., Folguera-Blasco, Núria, Cuyàs, Elisabet, Fernández-Arroyo, Salvador, Joven, Jorge, Alarcón, Tomás
Format:	Online
Language:	English
Published:	Impact Journals LLC 2016
Online Access:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4914261/

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