Flavokawain derivative FLS induced G2/M arrest and apoptosis on breast cancer MCF-7 cell line

Known as naturally occurring biologically active compounds, flavokawain A and B are the leading chalcones that possess anticancer properties. Another flavokawain derivative, (E)-1-(2′-Hydroxy-4′,6′-dimethoxyphenyl)-3-(4-methylthio)phenyl)prop-2-ene-1-one (FLS) was characterized with 1H-nuclear magne...

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Bibliographic Details
Main Authors: Ali, Norlaily Mohd, Akhtar, M Nadeem, Ky, Huynh, Lim, Kian Lam, Abu, Nadiah, Zareen, Seema, Ho, Wan Yong, Alan-Ong, Han Kiat, Tan, Sheau Wei, Alitheen, Noorjahan Banu, Ismail, Jamil bin, Yeap, Swee Keong, Kamarul, Tunku
Format: Online
Language:English
Published: Dove Medical Press 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4912327/