Implications of NQO1 in cancer therapy
NAD(P)H:quinone oxidoreductase (NQO1), an obligatory two-electron reductase, is a ubiquitous cytosolic enzyme that catalyzes the reduction of quinone substrates. The NQO1- mediated two-electron reduction of quinones can be either chemoprotection/detoxification or a chemotherapeutic response, dependi...
Main Authors: | , |
---|---|
Format: | Online |
Language: | English |
Published: |
Korean Society for Biochemistry and Molecular
Biology
2015
|
Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4911202/ |