Spatiotemporal plasticity of miRNAs functions: The miR-17-92 case

Spatiotemporal plasticity of miRNAs functions: The miR-17-92 case

The functional effect of a specific miRNA is tightly linked to the transcriptome, thus having the potential to elicit distinct outcomes in different cellular states. Our recent discovery of a dual role of the miR-17-92 cluster, which shifts from oncogene to tumor suppressor during lymphoma progressi...

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Main Authors: Bonaldi, Tiziana, Mihailovich, Marija
Format: Online
Language:English
Published: Taylor & Francis 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4909434/
id pubmed-4909434
recordtype oai_dc
spelling pubmed-49094342017-04-15 Spatiotemporal plasticity of miRNAs functions: The miR-17-92 case Bonaldi, Tiziana Mihailovich, Marija Author's View The functional effect of a specific miRNA is tightly linked to the transcriptome, thus having the potential to elicit distinct outcomes in different cellular states. Our recent discovery of a dual role of the miR-17-92 cluster, which shifts from oncogene to tumor suppressor during lymphoma progression, exemplifies the spatiotemporal plasticity of miRNAs. Taylor & Francis 2016-04-15 /pmc/articles/PMC4909434/ /pubmed/27314099 http://dx.doi.org/10.1080/23723556.2016.1156216 Text en © 2016 The Author(s). Published with license by Taylor & Francis Group, LLC http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. The moral rights of the named author(s) have been asserted.
repository_type Open Access Journal
institution_category Foreign Institution
institution US National Center for Biotechnology Information
building NCBI PubMed
collection Online Access
language English
format Online
author Bonaldi, Tiziana
Mihailovich, Marija
spellingShingle Bonaldi, Tiziana
Mihailovich, Marija
Spatiotemporal plasticity of miRNAs functions: The miR-17-92 case
author_facet Bonaldi, Tiziana
Mihailovich, Marija
author_sort Bonaldi, Tiziana
title Spatiotemporal plasticity of miRNAs functions: The miR-17-92 case
title_short Spatiotemporal plasticity of miRNAs functions: The miR-17-92 case
title_full Spatiotemporal plasticity of miRNAs functions: The miR-17-92 case
title_fullStr Spatiotemporal plasticity of miRNAs functions: The miR-17-92 case
title_full_unstemmed Spatiotemporal plasticity of miRNAs functions: The miR-17-92 case
title_sort spatiotemporal plasticity of mirnas functions: the mir-17-92 case
description The functional effect of a specific miRNA is tightly linked to the transcriptome, thus having the potential to elicit distinct outcomes in different cellular states. Our recent discovery of a dual role of the miR-17-92 cluster, which shifts from oncogene to tumor suppressor during lymphoma progression, exemplifies the spatiotemporal plasticity of miRNAs.
publisher Taylor & Francis
publishDate 2016
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4909434/
_version_ 1613595304779579392

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