Prediction of ribosome footprint profile shapes from transcript sequences

Motivation: Ribosome profiling is a useful technique for studying translational dynamics and quantifying protein synthesis. Applications of this technique have shown that ribosomes are not uniformly distributed along mRNA transcripts. Understanding how each transcript-specific distribution arises is...

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Main Authors: Liu, Tzu-Yu, Song, Yun S.
Format: Online
Language:English
Published: Oxford University Press 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4908337/
id pubmed-4908337
recordtype oai_dc
spelling pubmed-49083372016-06-17 Prediction of ribosome footprint profile shapes from transcript sequences Liu, Tzu-Yu Song, Yun S. Ismb 2016 Proceedings July 8 to July 12, 2016, Orlando, Florida Motivation: Ribosome profiling is a useful technique for studying translational dynamics and quantifying protein synthesis. Applications of this technique have shown that ribosomes are not uniformly distributed along mRNA transcripts. Understanding how each transcript-specific distribution arises is important for unraveling the translation mechanism. Oxford University Press 2016-06-15 2016-06-11 /pmc/articles/PMC4908337/ /pubmed/27307616 http://dx.doi.org/10.1093/bioinformatics/btw253 Text en © The Author 2016. Published by Oxford University Press. http://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
repository_type Open Access Journal
institution_category Foreign Institution
institution US National Center for Biotechnology Information
building NCBI PubMed
collection Online Access
language English
format Online
author Liu, Tzu-Yu
Song, Yun S.
spellingShingle Liu, Tzu-Yu
Song, Yun S.
Prediction of ribosome footprint profile shapes from transcript sequences
author_facet Liu, Tzu-Yu
Song, Yun S.
author_sort Liu, Tzu-Yu
title Prediction of ribosome footprint profile shapes from transcript sequences
title_short Prediction of ribosome footprint profile shapes from transcript sequences
title_full Prediction of ribosome footprint profile shapes from transcript sequences
title_fullStr Prediction of ribosome footprint profile shapes from transcript sequences
title_full_unstemmed Prediction of ribosome footprint profile shapes from transcript sequences
title_sort prediction of ribosome footprint profile shapes from transcript sequences
description Motivation: Ribosome profiling is a useful technique for studying translational dynamics and quantifying protein synthesis. Applications of this technique have shown that ribosomes are not uniformly distributed along mRNA transcripts. Understanding how each transcript-specific distribution arises is important for unraveling the translation mechanism.
publisher Oxford University Press
publishDate 2016
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4908337/
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