Fabrication of novel vesicles of triptolide for antirheumatoid activity with reduced toxicity in vitro and in vivo

Triptolide (TP) displays a strong immunosuppression function in immune-mediated diseases, especially in the treatment of rheumatoid arthritis. However, in addition to its medical and health-related functions, TP also exhibits diverse pharmacological side effects, for instance, liver and kidney toxic...

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Bibliographic Details
Main Authors: Zhang, Li, Wang, Tengteng, Li, Qiang, Huang, Jing, Xu, Hao, Li, Jinlong, Wang, Yongjun, Liang, Qianqian
Format: Online
Language:English
Published: Dove Medical Press 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4907735/