Standards for Cell Line Authentication and Beyond
Different genomic technologies have been applied to cell line authentication, but only one method (short tandem repeat [STR] profiling) has been the subject of a comprehensive and definitive standard (ASN-0002). Here we discuss the power of this document and why standards such as this are so critica...
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| Format: | Online |
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Public Library of Science
2016
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4907466/ |
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pubmed-49074662016-07-18 Standards for Cell Line Authentication and Beyond Almeida, Jamie L. Cole, Kenneth D. Plant, Anne L. Perspective Different genomic technologies have been applied to cell line authentication, but only one method (short tandem repeat [STR] profiling) has been the subject of a comprehensive and definitive standard (ASN-0002). Here we discuss the power of this document and why standards such as this are so critical for establishing the consensus technical criteria and practices that can enable progress in the fields of research that use cell lines. We also examine other methods that could be used for authentication and discuss how a combination of methods could be used in a holistic fashion to assess various critical aspects of the quality of cell lines. Public Library of Science 2016-06-14 /pmc/articles/PMC4907466/ /pubmed/27300367 http://dx.doi.org/10.1371/journal.pbio.1002476 Text en https://creativecommons.org/publicdomain/zero/1.0/ This is an open access article, free of all copyright, and may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose. The work is made available under the Creative Commons CC0 (https://creativecommons.org/publicdomain/zero/1.0/) public domain dedication. |
| repository_type |
Open Access Journal |
| institution_category |
Foreign Institution |
| institution |
US National Center for Biotechnology Information |
| building |
NCBI PubMed |
| collection |
Online Access |
| language |
English |
| format |
Online |
| author |
Almeida, Jamie L. Cole, Kenneth D. Plant, Anne L. |
| spellingShingle |
Almeida, Jamie L. Cole, Kenneth D. Plant, Anne L. Standards for Cell Line Authentication and Beyond |
| author_facet |
Almeida, Jamie L. Cole, Kenneth D. Plant, Anne L. |
| author_sort |
Almeida, Jamie L. |
| title |
Standards for Cell Line Authentication and Beyond |
| title_short |
Standards for Cell Line Authentication and Beyond |
| title_full |
Standards for Cell Line Authentication and Beyond |
| title_fullStr |
Standards for Cell Line Authentication and Beyond |
| title_full_unstemmed |
Standards for Cell Line Authentication and Beyond |
| title_sort |
standards for cell line authentication and beyond |
| description |
Different genomic technologies have been applied to cell line authentication, but only one method (short tandem repeat [STR] profiling) has been the subject of a comprehensive and definitive standard (ASN-0002). Here we discuss the power of this document and why standards such as this are so critical for establishing the consensus technical criteria and practices that can enable progress in the fields of research that use cell lines. We also examine other methods that could be used for authentication and discuss how a combination of methods could be used in a holistic fashion to assess various critical aspects of the quality of cell lines. |
| publisher |
Public Library of Science |
| publishDate |
2016 |
| url |
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4907466/ |
| _version_ |
1613594529997258752 |