Vascular Fibrosis in Aging and Hypertension: Molecular Mechanisms and Clinical Implications

Aging is the primary risk factor underlying hypertension and incident cardiovascular disease. With aging, the vasculature undergoes structural and functional changes characterized by endothelial dysfunction, wall thickening, reduced distensibility, and arterial stiffening. Vascular stiffness results...

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Bibliographic Details
Main Authors: Harvey, Adam, Montezano, Augusto C., Lopes, Rheure Alves, Rios, Francisco, Touyz, Rhian M.
Format: Online
Language:English
Published: Pulsus Group 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4906153/