Overcoming chemo/radio-resistance of pancreatic cancer by inhibiting STAT3 signaling
Chemo/radio-therapy resistance to the deadly pancreatic cancer is mainly due to the failure to kill pancreatic cancer stem cells (CSCs). Signal transducer and activator of transcription 3 (STAT3) is activated in pancreatic CSCs and, therefore, may be a valid target for overcoming therapeutic resista...
Main Authors: | , , , , , , , , , , , |
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Format: | Online |
Language: | English |
Published: |
Impact Journals LLC
2016
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4905505/ |