Loss of oncogenic miR-155 in tumor cells promotes tumor growth by enhancing C/EBP-β-mediated MDSC infiltration

Loss of oncogenic miR-155 in tumor cells promotes tumor growth by enhancing C/EBP-β-mediated MDSC infiltration

The oncogenic role of microRNA-155 (miR-155) in leukemia is well established but its role in other cancers, especially breast cancer, is gradually emerging. In this study we examined the effect of mir-155 loss in a well-characterized spontaneous breast cancer mouse model where Brca1 and Trp53 are de...

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Bibliographic Details
Main Authors: Kim, Sinae, Song, Jin Hoi, Kim, Seokho, Qu, Peng, Martin, Betty K., Sehareen, Waheed S., Haines, Diana C., Lin, Pengnian C., Sharan, Shyam K., Chang, Suhwan
Format: Online
Language:English
Published: Impact Journals LLC 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4905460/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4905460/

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