Immunogenicity and safety of xenogeneic vascular endothelial growth factor receptor-2 DNA vaccination in mice and dogs
Vascular endothelial growth factor receptor-2 (VEGFR-2) is an attractive target in oncology due to its crucial role in angiogenesis. In this study a DNA vaccine coding for human VEGFR-2 was evaluated in healthy mice and dogs, administered by intradermal injection and electroporation. In mice, three...
Main Authors: | , , , |
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Format: | Online |
Language: | English |
Published: |
Impact Journals LLC
2016
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4905448/ |