Unraveling the therapeutic potential of the LncRNA-dependent noncanonical Hedgehog pathway in cancer

Acquired resistance to Hedgehog pathway inhibitors has been reported in the clinical setting and upregulation of noncanonical Hedgehog signaling is one of the major underlying mechanisms behind this resistance. As demonstrated in our recent study, greater clinical efficacy might be achieved by focus...

Full description

Bibliographic Details
Main Authors: Xing, Zhen, Lin, Chunru, Yang, Liuqing
Format: Online
Language:English
Published: Taylor & Francis 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4905365/