The BARD1/HP1 interaction: Another clue to heterochromatin involvement in homologous recombination

Chromatin compaction represents a barrier for the repair of DNA double-strand breaks (DSBs). However, heterochromatin components are also required for DSB repair by homologous recombination. The BARD1/HP1 interaction, required for the retention of BRCA1, CTIP, and RAD51 at DSB sites, may play a crit...

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Bibliographic Details
Main Authors: Fukuda, Takayo, Tsuruga, Tomoko, Kuroda, Takako, Takeuchi, Jun, Wu, Wenwen, Ohta, Tomohiko
Format: Online
Language:English
Published: Taylor & Francis 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4905335/