The BARD1/HP1 interaction: Another clue to heterochromatin involvement in homologous recombination
Chromatin compaction represents a barrier for the repair of DNA double-strand breaks (DSBs). However, heterochromatin components are also required for DSB repair by homologous recombination. The BARD1/HP1 interaction, required for the retention of BRCA1, CTIP, and RAD51 at DSB sites, may play a crit...
Main Authors: | , , , , , |
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Format: | Online |
Language: | English |
Published: |
Taylor & Francis
2015
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4905335/ |