Redox regulation of Smac mimetic-induced cell death
Cell death and survival programs are controlled by the cellular redox state, which is typically dysregulated during oncogenesis. A recent study reports that the inhibition of antioxidant defenses resulting from glutathione depletion can prime acute lymphoblastic leukemia cells for death induced by S...
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Format: | Online |
Language: | English |
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Taylor & Francis
2015
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4905326/ |