Oncogenic and oncosuppressive signal transduction at mitochondria-associated endoplasmic reticulum membranes

The different mechanisms employed by proto-oncogenes and tumor suppressors to regulate cell death pathways are strictly linked to their localization. In addition to the canonical control of apoptosis at a transcriptional/nuclear level, intracellular zones are emerging as pivotal sites for the activi...

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Bibliographic Details
Main Authors: Marchi, Saverio, Giorgi, Carlotta, Oparka, Monika, Duszynski, Jerzy, Wieckowski, Mariusz R, Pinton, Paolo
Format: Online
Language:English
Published: Taylor & Francis 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4905193/