Regulation of intestinal homeostasis and tumorigenesis by the transcriptional coregulator RIP140
Colon cancer frequently results from mutations that constitutively activate the Wnt signaling pathway, a major target being the tumor suppressor gene adenomatous polyposis coli (APC). We recently identified the transcription factor RIP140 as a new inducer of APC gene transcription that inhibits colo...
Main Authors: | , |
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Format: | Online |
Language: | English |
Published: |
Taylor & Francis
2014
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4905177/ |