Regulation of intestinal homeostasis and tumorigenesis by the transcriptional coregulator RIP140

Colon cancer frequently results from mutations that constitutively activate the Wnt signaling pathway, a major target being the tumor suppressor gene adenomatous polyposis coli (APC). We recently identified the transcription factor RIP140 as a new inducer of APC gene transcription that inhibits colo...

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Bibliographic Details
Main Authors: Cavaillès, Vincent, Lapierre, Marion
Format: Online
Language:English
Published: Taylor & Francis 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4905177/