Necroptosis: Fifty shades of RIPKs
Apoptosis and necroptosis are 2 major, yet distinct, forms of regulated cell death. Whereas apoptosis requires caspase protease function, necroptosis requires activation of the receptor interacting protein kinases 1 (RIPK1) and RIPK3. Following activation, RIPK3 phosphorylates mixed-lineage kinase d...
Main Authors: | , |
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Format: | Online |
Language: | English |
Published: |
Taylor & Francis
2014
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4905023/ |