Correlation of Apobec Mrna Expression with overall Survival and pd-l1 Expression in Urothelial Carcinoma

Metastatic urothelial carcinoma (mUC) has a very high mutational rate and is associated with an APOBEC mutation signature. We examined the correlation of APOBEC expression with overall survival (OS) and PD-L1 expression in a cohort of 73 mUC patients. mRNA expression of APOBEC3 family of genes (A3A,...

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Bibliographic Details
Main Authors: Mullane, Stephanie A., Werner, Lillian, Rosenberg, Jonathan, Signoretti, Sabina, Callea, Marcella, Choueiri, Toni K., Freeman, Gordon J., Bellmunt, Joaquim
Format: Online
Language:English
Published: Nature Publishing Group 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4901342/