STAT3 regulates hypoxia-induced epithelial mesenchymal transition in oesophageal squamous cell cancer

Hypoxia plays a key role in tumour initiation and metastasis; one of the mechanisms is to induce epithelial-mesenchymal transition (EMT). Signal transducer and activator of transcription 3 (STAT3) is involved in EMT by regulating the transcriptional regulators of E-cadherin, the biomarker of EMT. Un...

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Bibliographic Details
Main Authors: CUI, YAO, LI, YUN-YUN, LI, JIAN, ZHANG, HONG-YAN, WANG, FENG, BAI, XUE, LI, SHAN-SHAN
Format: Online
Language:English
Published: D.A. Spandidos 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4899013/