Immunoregulatory Effects of Everolimus on In Vitro Alloimmune Responses

Everolimus (EVL) is a novel mTOR-inhibitor similar to sirolimus (SRL) that is used in organ transplant recipients, often in combination with tacrolimus (TAC) or mycophenolate (MPA). The current study aims to determine its effects on regulatory T cells. Increasing concentrations of EVL, MPA and TAC a...

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Bibliographic Details
Main Authors: Levitsky, Josh, Miller, Joshua, Huang, Xuemei, Gallon, Lorenzo, Leventhal, Joseph R., Mathew, James M.
Format: Online
Language:English
Published: Public Library of Science 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4898829/