Involvement of human ribosomal proteins in nucleolar structure and p53-dependent nucleolar stress

Involvement of human ribosomal proteins in nucleolar structure and p53-dependent nucleolar stress

The nucleolus is a potent disease biomarker and a target in cancer therapy. Ribosome biogenesis is initiated in the nucleolus where most ribosomal (r-) proteins assemble onto precursor rRNAs. Here we systematically investigate how depletion of each of the 80 human r-proteins affects nucleolar struct...

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Bibliographic Details
Main Authors: Nicolas, Emilien, Parisot, Pascaline, Pinto-Monteiro, Celina, de Walque, Roxane, De Vleeschouwer, Christophe, Lafontaine, Denis L. J.
Format: Online
Language:English
Published: Nature Publishing Group 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4897761/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4897761/

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