CRF receptor 1 antagonism and brain distribution of active components contribute to the ameliorative effect of rikkunshito on stress-induced anorexia

CRF receptor 1 antagonism and brain distribution of active components contribute to the ameliorative effect of rikkunshito on stress-induced anorexia

Rikkunshito (RKT), a Kampo medicine, has been reported to show an ameliorative effect on sustained hypophagia after novelty stress exposure in aged mice through serotonin 2C receptor (5-HT2CR) antagonism. We aimed to determine (1) whether the activation of anorexigenic neurons, corticotropin-releasi...

Full description

Bibliographic Details
Main Authors: Mogami, Sachiko, Sadakane, Chiharu, Nahata, Miwa, Mizuhara, Yasuharu, Yamada, Chihiro, Hattori, Tomohisa, Takeda, Hiroshi
Format: Online
Language:English
Published: Nature Publishing Group 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4897628/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4897628/

Similar Items