BluePyOpt: Leveraging Open Source Software and Cloud Infrastructure to Optimise Model Parameters in Neuroscience

At many scales in neuroscience, appropriate mathematical models take the form of complex dynamical systems. Parameterizing such models to conform to the multitude of available experimental constraints is a global non-linear optimisation problem with a complex fitness landscape, requiring numerical t...

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Bibliographic Details
Main Authors: Van Geit, Werner, Gevaert, Michael, Chindemi, Giuseppe, Rössert, Christian, Courcol, Jean-Denis, Muller, Eilif B., Schürmann, Felix, Segev, Idan, Markram, Henry
Format: Online
Language:English
Published: Frontiers Media S.A. 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4896051/