Hsf1 and Hsp90 orchestrate temperature-dependent global transcriptional remodelling and chromatin architecture in Candida albicans

Hsf1 and Hsp90 orchestrate temperature-dependent global transcriptional remodelling and chromatin architecture in Candida albicans

Fever is a universal response to infection, and opportunistic pathogens such as Candida albicans have evolved complex circuitry to sense and respond to heat. Here we harness RNA-seq and ChIP-seq to discover that the heat shock transcription factor, Hsf1, binds distinct motifs in nucleosome-depleted...

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Bibliographic Details
Main Authors: Leach, Michelle D., Farrer, Rhys A., Tan, Kaeling, Miao, Zhengqiang, Walker, Louise A., Cuomo, Christina A., Wheeler, Robert T., Brown, Alistair J. P., Wong, Koon Ho, Cowen, Leah E.
Format: Online
Language:English
Published: Nature Publishing Group 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4894976/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4894976/

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