Detailed functional analysis of two clinical glucose-6-phosphate dehydrogenase (G6PD) variants, G6PDViangchan and G6PDViangchan + Mahidol: Decreased stability and catalytic efficiency contribute to the clinical phenotype
Deficiency of glucose-6-phosphate dehydrogenase (G6PD) is an X-linked hereditary genetic defect that is the most common polymorphism and enzymopathy in humans. To investigate functional properties of two clinical variants, G6PDViangchan and G6PDViangchan + Mahidol, these two mutants were created by...
| Main Authors: | , , , , , |
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| Format: | Online |
| Language: | English |
| Published: |
Academic Press
2016
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4894296/ |