Somato-axodendritic release of oxytocin into the brain due to calcium amplification is essential for social memory

Oxytocin (OT) is released into the brain from the cell soma, axons, and dendrites of neurosecretory cells in the hypothalamus. Locally released OT can activate OT receptors, form inositol-1,4,5-trisphosphate and elevate intracellular free calcium (Ca2+) concentrations [(Ca2+)i] in self and neighbori...

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Bibliographic Details
Main Author: Higashida, Haruhiro
Format: Online
Language:English
Published: Springer Japan 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4893072/