Spontaneous shaker rat mutant – a new model for X-linked tremor/ataxia

The shaker rat is an X-linked recessive spontaneous model of progressive Purkinje cell (PC) degeneration exhibiting a shaking ataxia and wide stance. Generation of Wistar Furth (WF)/Brown Norwegian (BN) F1 hybrids and genetic mapping of F2 sib-sib offspring using polymorphic markers narrowed the can...

Full description

Bibliographic Details
Main Authors: Figueroa, Karla P., Paul, Sharan, Calì, Tito, Lopreiato, Raffaele, Karan, Sukanya, Frizzarin, Martina, Ames, Darren, Zanni, Ginevra, Brini, Marisa, Dansithong, Warunee, Milash, Brett, Scoles, Daniel R., Carafoli, Ernesto, Pulst, Stefan M.
Format: Online
Language:English
Published: The Company of Biologists Ltd 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4892658/