Conessine Interferes with Oxidative Stress-Induced C2C12 Myoblast Cell Death through Inhibition of Autophagic Flux

Conessine, a steroidal alkaloid isolated from Holarrhena floribunda, has anti-malarial activity and interacts with the histamine H3 receptor. However, the cellular effects of conessine are poorly understood. Accordingly, we evaluated the involvement of conessine in the regulation of autophagy. We se...

Full description

Bibliographic Details
Main Authors: Kim, Hyunju, Lee, Kang Il, Jang, Minsu, Namkoong, Sim, Park, Rackhyun, Ju, Hyunwoo, Choi, Inho, Oh, Won Keun, Park, Junsoo
Format: Online
Language:English
Published: Public Library of Science 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4892631/