PPAR-pan activation induces hepatic oxidative stress and lipidomic remodelling

The peroxisome proliferator-activated receptors (PPARs) are ligand activated nuclear receptors that regulate cellular homoeostasis and metabolism. PPARs control the expression of genes involved in fatty-acid and lipid metabolism. Despite evidence showing beneficial effects of their activation in the...

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Bibliographic Details
Main Authors: Ament, Zsuzsanna, West, James A., Stanley, Elizabeth, Ashmore, Tom, Roberts, Lee D., Wright, Jayne, Nicholls, Andrew W., Griffin, Julian L.
Format: Online
Language:English
Published: Elsevier Science 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4891066/