Irsogladine maleate, a gastric mucosal protectant, suppresses intestinal polyp development in Apc-mutant mice

This study aimed to identify gastric mucosal protectants that suppress intestinal tumorigenesis in a mouse model. We chose six gastric mucosal protectants (ecabet sodium hydrate, irsogladine maleate, rebamipide, sofalcone, teprenone and troxipide) and examined their effects on the activity of oxidat...

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Bibliographic Details
Main Authors: Onuma, Wakana, Tomono, Susumu, Miyamoto, Shinngo, Fujii, Gen, Hamoya, Takahiro, Fujimoto, Kyoko, Miyoshi, Noriyuki, Fukai, Fumio, Wakabayashi, Keiji, Mutoh, Michihiro
Format: Online
Language:English
Published: Impact Journals LLC 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4890993/