Cyclical DNA Methylation and Histone Changes Are Induced by LPS to Activate COX-2 in Human Intestinal Epithelial Cells

Cyclical DNA Methylation and Histone Changes Are Induced by LPS to Activate COX-2 in Human Intestinal Epithelial Cells

Bacterial lipopolysaccharide (LPS) induces release of inflammatory mediators both in immune and epithelial cells. We investigated whether changes of epigenetic marks, including selected histone modification and DNA methylation, may drive or accompany the activation of COX-2 gene in HT-29 human intes...

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Bibliographic Details
Main Authors: Angrisano, Tiziana, Pero, Raffaela, Brancaccio, Mariarita, Coretti, Lorena, Florio, Ermanno, Pezone, Antonio, Calabrò, Viola, Falco, Geppino, Keller, Simona, Lembo, Francesca, Avvedimento, Vittorio Enrico, Chiariotti, Lorenzo
Format: Online
Language:English
Published: Public Library of Science 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4890762/

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