Flt1/VEGFR1 heterozygosity causes transient embryonic edema

Flt1/VEGFR1 heterozygosity causes transient embryonic edema

Vascular endothelial growth factor-A is a major player in vascular development and a potent vascular permeability factor under physiological and pathological conditions by binding to a decoy receptor Flt1 and its primary receptor Flk1. In this study, we show that Flt1 heterozygous (Flt1+/−) mouse em...

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Bibliographic Details
Main Authors: Otowa, Yasunori, Moriwaki, Kazumasa, Sano, Keigo, Shirakabe, Masanori, Yonemura, Shigenobu, Shibuya, Masabumi, Rossant, Janet, Suda, Toshio, Kakeji, Yoshihiro, Hirashima, Masanori
Format: Online
Language:English
Published: Nature Publishing Group 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4890026/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4890026/

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