Site-Directed Genome Knockout in Chicken Cell Line and Embryos Can Use CRISPR/Cas Gene Editing Technology

The present study established an efficient genome editing approach for the construction of stable transgenic cell lines of the domestic chicken (Gallus gallus domesticus). Our objectives were to facilitate the breeding of high-yield, high-quality chicken strains, and to investigate gene function in...

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Bibliographic Details
Main Authors: Zuo, Qisheng, Wang, Yinjie, Cheng, Shaoze, Lian, Chao, Tang, Beibei, Wang, Fei, Lu, Zhenyu, Ji, Yanqing, Zhao, Ruifeng, Zhang, Wenhui, Jin, Kai, Song, Jiuzhou, Zhang, Yani, Li, Bichun
Format: Online
Language:English
Published: Genetics Society of America 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4889674/