Local Ancestry Inference in a Large US-Based Hispanic/Latino Study: Hispanic Community Health Study/Study of Latinos (HCHS/SOL)

We estimated local ancestry on the autosomes and X chromosome in a large US-based study of 12,793 Hispanic/Latino individuals using the RFMix method, and we compared different reference panels and approaches to local ancestry estimation on the X chromosome by means of Mendelian inconsistency rates a...

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Bibliographic Details
Main Authors: Browning, Sharon R., Grinde, Kelsey, Plantinga, Anna, Gogarten, Stephanie M., Stilp, Adrienne M., Kaplan, Robert C., Avilés-Santa, M. Larissa, Browning, Brian L., Laurie, Cathy C.
Format: Online
Language:English
Published: Genetics Society of America 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4889649/