Extracellular interactions and ligand degradation shape the nodal morphogen gradient

The correct distribution and activity of secreted signaling proteins called morphogens is required for many developmental processes. Nodal morphogens play critical roles in embryonic axis formation in many organisms. Models proposed to generate the Nodal gradient include diffusivity, ligand processi...

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Bibliographic Details
Main Authors: Wang, Yin, Wang, Xi, Wohland, Thorsten, Sampath, Karuna
Format: Online
Language:English
Published: eLife Sciences Publications, Ltd 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4887204/