Generation of Functional Beta-Like Cells from Human Exocrine Pancreas

Transcription factor mediated lineage reprogramming of human pancreatic exocrine tissue could conceivably provide an unlimited supply of islets for transplantation in the treatment of diabetes. Exocrine tissue can be efficiently reprogrammed to islet-like cells using a cocktail of transcription fact...

Full description

Bibliographic Details
Main Authors: Lima, Maria J., Muir, Kenneth R., Docherty, Hilary M., McGowan, Neil W. A., Forbes, Shareen, Heremans, Yves, Heimberg, Harry, Casey, John, Docherty, Kevin
Format: Online
Language:English
Published: Public Library of Science 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4887015/