Assessment of polygenic effects links primary open-angle glaucoma and age-related macular degeneration

Primary open-angle glaucoma (POAG) and age-related macular degeneration (AMD) are leading causes of irreversible blindness. Several loci have been mapped using genome-wide association studies. Until very recently, there was no recognized overlap in the genetic contribution to AMD and POAG. At genome...

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Bibliographic Details
Main Authors: Cuellar-Partida, Gabriel, Craig, Jamie E., Burdon, Kathryn P., Wang, Jie Jin, Vote, Brendan J., Souzeau, Emmanuelle, McAllister, Ian L., Isaacs, Timothy, Lake, Stewart, Mackey, David A., Constable, Ian J., Mitchell, Paul, Hewitt, Alex W., MacGregor, Stuart
Format: Online
Language:English
Published: Nature Publishing Group 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4886254/