Inactivating Mutations in GNA13 and RHOA in Burkitt’s Lymphoma and Diffuse Large B cell Lymphoma: A Tumor Suppressor Function for the Gα13/RhoA Axis in B Cells

Inactivating Mutations in GNA13 and RHOA in Burkitt’s Lymphoma and Diffuse Large B cell Lymphoma: A Tumor Suppressor Function for the Gα13/RhoA Axis in B Cells

G-proteins and their cognate G-protein coupled receptors (GPCRs) function as critical signal transduction molecules that regulate cell survival, proliferation, motility and differentiation. The aberrant expression and/or function of these molecules have been linked to the growth, progression and met...

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Bibliographic Details
Main Authors: O’Hayre, Morgan, Inoue, Asuka, Kufareva, Irina, Wang, Zhiyong, Mikelis, Constantinos M., Drummond, Rebecca A., Avino, Silvia, Finkel, Kira, Kalim, Khalid, DiPasquale, Giovanni, Guo, Fukun, Aoki, Junken, Zheng, Yi, Lionakis, Michail S., Molinolo, Alfredo A., Gutkind, J. Silvio
Format: Online
Language:English
Published: 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4885800/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4885800/

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