Oncogenic mTOR signaling recruits myeloid-derived suppressor cells to promote tumor initiation

Oncogenic mTOR signaling recruits myeloid-derived suppressor cells to promote tumor initiation

Myeloid-derived suppressor cells (MDSCs) play critical roles in primary and metastatic cancer progression. While MDSC regulation is widely variable even within patients harboring the same type of malignancy, the mechanisms governing such heterogeneity are largely unknown. Here, integrating human tum...

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Bibliographic Details
Main Authors: Welte, Thomas, Kim, Ik Sun, Tian, Lin, Gao, Xia, Wang, Hai, Li, June, Holdman, Xue B., Herschkowitz, Jason I., Pond, Adam, Xie, Guorui, Kurley, Sarah, Nguyen, Tuan, Liao, Lan, Dobrolecki, Lacey E., Mo, Qianxing, Edwards, Dean P., Huang, Shixia, Xin, Li, Xu, Jianming, Li, Yi, Lewis, Michael T., Wang, Tian, Westbrook, Thomas F., Rosen, Jeffrey M., Zhang, Xiang H.-F.
Format: Online
Language:English
Published: 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4884142/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4884142/

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