Rituximab for Rheumatoid Arthritis
Rituximab is a chimeric monoclonal antibody directed at the CD20 molecule on the surfaces of some but not all B cells. It depletes almost all peripheral B cells, but other niches of B cells are variably depleted, including synovium. Its mechanism of action in rheumatoid arthritis (RA) is only partia...
| Main Authors: | , |
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| Format: | Online |
| Language: | English |
| Published: |
Springer Healthcare
2015
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4883263/ |