NAMPT knockdown attenuates atherosclerosis and promotes reverse cholesterol transport in ApoE KO mice with high-fat-induced insulin resistance

NAMPT has been suggested association with atherosclerosis and insulin resistance. However, the impact of NAMPT on atherosclerosis remained unknown. Therefore, the objective of this study was to use a NAMPT loss-of-function approach to investigate the effect of NAMPT on atherosclerosis in hypercholes...

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Bibliographic Details
Main Authors: Li, Shengbing, Wang, Cong, Li, Ke, Li, Ling, Tian, Mingyuan, Xie, Jing, Yang, Mengliu, Jia, Yanjun, He, Junying, Gao, Lin, Boden, Guenther, Liu, Hua, Yang, Gangyi
Format: Online
Language:English
Published: Nature Publishing Group 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4882618/