Lack of Phenotypical and Morphological Evidences of Endothelial to Hematopoietic Transition in the Murine Embryonic Head during Hematopoietic Stem Cell Emergence

During mouse ontogeny, hematopoietic cells arise from specialized endothelial cells, i.e., the hemogenic endothelium, and form clusters in the lumen of arterial vessels. Hemogenic endothelial cells have been observed in several embryonic tissues, such as the dorsal aorta, the placenta and the yolk s...

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Bibliographic Details
Main Authors: Iizuka, Kazuhide, Yokomizo, Tomomasa, Watanabe, Naoki, Tanaka, Yosuke, Osato, Motomi, Takaku, Tomoiku, Komatsu, Norio
Format: Online
Language:English
Published: Public Library of Science 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4882078/