First-in-class small molecule potentiators of cancer virotherapy

First-in-class small molecule potentiators of cancer virotherapy

The use of engineered viral strains such as gene therapy vectors and oncolytic viruses (OV) to selectively destroy cancer cells is poised to make a major impact in the clinic and revolutionize cancer therapy. In particular, several studies have shown that OV therapy is safe and well tolerated in hum...

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Bibliographic Details
Main Authors: Dornan, Mark H., Krishnan, Ramya, Macklin, Andrew M., Selman, Mohammed, El Sayes, Nader, Son, Hwan Hee, Davis, Colin, Chen, Andrew, Keillor, Kerkeslin, Le, Penny J., Moi, Christina, Ou, Paula, Pardin, Christophe, Canez, Carlos R., Le Boeuf, Fabrice, Bell, John C., Smith, Jeffrey C., Diallo, Jean-Simon, Boddy, Christopher N.
Format: Online
Language:English
Published: Nature Publishing Group 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4880900/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4880900/

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