Functional Connectivity Modulation by Acupuncture in Patients with Bell's Palsy

Bell's palsy (BP), an acute unilateral facial paralysis, is frequently treated with acupuncture in many countries. However, the mechanism of treatment is not clear so far. In order to explore the potential mechanism, 22 healthy volunteers and 17 BP patients with different clinical duration were...

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Main Authors:	Bian, Yunpeng, He, Xiaoxuan, Hu, Sheng, Li, Chuanfu, Xu, Chunsheng, Kan, Hongxing, Xue, Qiuju, Yang, Jun, Qiu, Bensheng
Format:	Online
Language:	English
Published:	Hindawi Publishing Corporation 2016
Online Access:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4880700/

id	pubmed-4880700
recordtype	oai_dc
spelling	pubmed-48807002016-06-12 Functional Connectivity Modulation by Acupuncture in Patients with Bell's Palsy Bian, Yunpeng He, Xiaoxuan Hu, Sheng Li, Chuanfu Xu, Chunsheng Kan, Hongxing Xue, Qiuju Yang, Jun Qiu, Bensheng Research Article Bell's palsy (BP), an acute unilateral facial paralysis, is frequently treated with acupuncture in many countries. However, the mechanism of treatment is not clear so far. In order to explore the potential mechanism, 22 healthy volunteers and 17 BP patients with different clinical duration were recruited. The resting-state functional magnetic resonance imaging scans were conducted before and after acupuncture at LI4 (Hegu), respectively. By comparing BP-induced functional connectivity (FC) changes with acupuncture-induced FC changes in the patients, the abnormal increased FC that could be reduced by acupuncture was selected. The FC strength of the selected FC at various stages was analyzed subsequently. Our results show that FC modulation of acupuncture is specific and consistent with the tendency of recovery. Therefore, we propose that FC modulation by acupuncture may be beneficial to recovery from the disease. Hindawi Publishing Corporation 2016 2016-05-12 /pmc/articles/PMC4880700/ /pubmed/27293461 http://dx.doi.org/10.1155/2016/5928758 Text en Copyright © 2016 Yunpeng Bian et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
repository_type	Open Access Journal
institution_category	Foreign Institution
institution	US National Center for Biotechnology Information
building	NCBI PubMed
collection	Online Access
language	English
format	Online
author	Bian, Yunpeng He, Xiaoxuan Hu, Sheng Li, Chuanfu Xu, Chunsheng Kan, Hongxing Xue, Qiuju Yang, Jun Qiu, Bensheng
spellingShingle	Bian, Yunpeng He, Xiaoxuan Hu, Sheng Li, Chuanfu Xu, Chunsheng Kan, Hongxing Xue, Qiuju Yang, Jun Qiu, Bensheng Functional Connectivity Modulation by Acupuncture in Patients with Bell's Palsy
author_facet	Bian, Yunpeng He, Xiaoxuan Hu, Sheng Li, Chuanfu Xu, Chunsheng Kan, Hongxing Xue, Qiuju Yang, Jun Qiu, Bensheng
author_sort	Bian, Yunpeng
title	Functional Connectivity Modulation by Acupuncture in Patients with Bell's Palsy
title_short	Functional Connectivity Modulation by Acupuncture in Patients with Bell's Palsy
title_full	Functional Connectivity Modulation by Acupuncture in Patients with Bell's Palsy
title_fullStr	Functional Connectivity Modulation by Acupuncture in Patients with Bell's Palsy
title_full_unstemmed	Functional Connectivity Modulation by Acupuncture in Patients with Bell's Palsy
title_sort	functional connectivity modulation by acupuncture in patients with bell's palsy
description	Bell's palsy (BP), an acute unilateral facial paralysis, is frequently treated with acupuncture in many countries. However, the mechanism of treatment is not clear so far. In order to explore the potential mechanism, 22 healthy volunteers and 17 BP patients with different clinical duration were recruited. The resting-state functional magnetic resonance imaging scans were conducted before and after acupuncture at LI4 (Hegu), respectively. By comparing BP-induced functional connectivity (FC) changes with acupuncture-induced FC changes in the patients, the abnormal increased FC that could be reduced by acupuncture was selected. The FC strength of the selected FC at various stages was analyzed subsequently. Our results show that FC modulation of acupuncture is specific and consistent with the tendency of recovery. Therefore, we propose that FC modulation by acupuncture may be beneficial to recovery from the disease.
publisher	Hindawi Publishing Corporation
publishDate	2016
url	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4880700/
_version_	1613584288627818496

Functional Connectivity Modulation by Acupuncture in Patients with Bell's Palsy

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