Review: The HSP90 molecular chaperone—an enigmatic ATPase
The HSP90 molecular chaperone is involved in the activation and cellular stabilization of a range of ‘client’ proteins, of which oncogenic protein kinases and nuclear steroid hormone receptors are of particular biomedical significance. Work over the last two decades has revealed a conformational cyc...
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Format: | Online |
Language: | English |
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John Wiley and Sons Inc.
2016
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4879513/ |