Antitrypanosomal Activities and Mechanisms of Action of Novel Tetracyclic Iridoids from Morinda lucida Benth.

Trypanosoma brucei parasites are kinetoplastid protozoa that devastate the health and economic well-being of millions of people in Africa through the disease human African trypanosomiasis (HAT). New chemotherapy has been eagerly awaited due to severe side effects and the drug resistance issues plagu...

Full description

Bibliographic Details
Main Authors: Kwofie, Kofi D., Tung, Nguyen Huu, Suzuki-Ohashi, Mitsuko, Amoa-Bosompem, Michael, Adegle, Richard, Sakyiamah, Maxwell M., Ayertey, Frederick, Owusu, Kofi Baffour-Awuah, Tuffour, Isaac, Atchoglo, Philip, Frempong, Kwadwo K., Anyan, William K., Uto, Takuhiro, Morinaga, Osamu, Yamashita, Taizo, Aboagye, Frederic, Appiah, Alfred A., Appiah-Opong, Regina, Nyarko, Alexander K., Yamaguchi, Yasuchika, Edoh, Dominic, Koram, Kwadwo A., Yamaoka, Shoji, Boakye, Daniel A., Ohta, Nobuo, Shoyama, Yukihiro, Ayi, Irene
Format: Online
Language:English
Published: American Society for Microbiology 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4879371/