Quantitative assessment of the stent/scaffold strut embedment analysis by optical coherence tomography
The degree of stent/scaffold embedment could be a surrogate parameter of the vessel wall-stent/scaffold interaction and could have biological implications in the vascular response. We have developed a new specific software for the quantitative evaluation of embedment of struts by optical coherence t...
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| Format: | Online |
| Language: | English |
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Springer Netherlands
2016
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4879175/ |
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pubmed-48791752016-06-21 Quantitative assessment of the stent/scaffold strut embedment analysis by optical coherence tomography Sotomi, Yohei Tateishi, Hiroki Suwannasom, Pannipa Dijkstra, Jouke Eggermont, Jeroen Liu, Shengnan Tenekecioglu, Erhan Zheng, Yaping Abdelghani, Mohammad Cavalcante, Rafael de Winter, Robbert J. Wykrzykowska, Joanna J. Onuma, Yoshinobu Serruys, Patrick W. Kimura, Takeshi Original Paper The degree of stent/scaffold embedment could be a surrogate parameter of the vessel wall-stent/scaffold interaction and could have biological implications in the vascular response. We have developed a new specific software for the quantitative evaluation of embedment of struts by optical coherence tomography (OCT). In the present study, we described the algorithm of the embedment analysis and its reproducibility. The degree of embedment was evaluated as the ratio of the embedded part versus the whole strut height and subdivided into quartiles. The agreement and the inter- and intra-observer reproducibility were evaluated using the kappa and the interclass correlation coefficient (ICC). A total of 4 pullbacks of OCT images in 4 randomly selected coronary lesions with 3.0 × 18 mm devices [2 lesions with Absorb BVS and 2 lesions with XIENCE (both from Abbott Vascular, Santa Clara, CA, USA)] from Absorb Japan trial were evaluated by two investigators with QCU-CMS software version 4.69 (Leiden University Medical Center, Leiden, The Netherlands). Finally, 1481 polymeric struts in 174 cross-sections and 1415 metallic struts in 161 cross-sections were analyzed. Inter- and intra-observer reproducibility of quantitative measurements of embedment ratio and categorical assessment of embedment in Absorb BVS and XIENCE had excellent agreement with ICC ranging from 0.958 to 0.999 and kappa ranging from 0.850 to 0.980. The newly developed embedment software showed excellent reproducibility. Computer-assisted embedment analysis could be a feasible tool to assess the strut penetration into the vessel wall that could be a surrogate of acute injury caused by implantation of devices. Springer Netherlands 2016-02-22 2016 /pmc/articles/PMC4879175/ /pubmed/26898315 http://dx.doi.org/10.1007/s10554-016-0856-6 Text en © The Author(s) 2016 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. |
| repository_type |
Open Access Journal |
| institution_category |
Foreign Institution |
| institution |
US National Center for Biotechnology Information |
| building |
NCBI PubMed |
| collection |
Online Access |
| language |
English |
| format |
Online |
| author |
Sotomi, Yohei Tateishi, Hiroki Suwannasom, Pannipa Dijkstra, Jouke Eggermont, Jeroen Liu, Shengnan Tenekecioglu, Erhan Zheng, Yaping Abdelghani, Mohammad Cavalcante, Rafael de Winter, Robbert J. Wykrzykowska, Joanna J. Onuma, Yoshinobu Serruys, Patrick W. Kimura, Takeshi |
| spellingShingle |
Sotomi, Yohei Tateishi, Hiroki Suwannasom, Pannipa Dijkstra, Jouke Eggermont, Jeroen Liu, Shengnan Tenekecioglu, Erhan Zheng, Yaping Abdelghani, Mohammad Cavalcante, Rafael de Winter, Robbert J. Wykrzykowska, Joanna J. Onuma, Yoshinobu Serruys, Patrick W. Kimura, Takeshi Quantitative assessment of the stent/scaffold strut embedment analysis by optical coherence tomography |
| author_facet |
Sotomi, Yohei Tateishi, Hiroki Suwannasom, Pannipa Dijkstra, Jouke Eggermont, Jeroen Liu, Shengnan Tenekecioglu, Erhan Zheng, Yaping Abdelghani, Mohammad Cavalcante, Rafael de Winter, Robbert J. Wykrzykowska, Joanna J. Onuma, Yoshinobu Serruys, Patrick W. Kimura, Takeshi |
| author_sort |
Sotomi, Yohei |
| title |
Quantitative assessment of the stent/scaffold strut embedment analysis by optical coherence tomography |
| title_short |
Quantitative assessment of the stent/scaffold strut embedment analysis by optical coherence tomography |
| title_full |
Quantitative assessment of the stent/scaffold strut embedment analysis by optical coherence tomography |
| title_fullStr |
Quantitative assessment of the stent/scaffold strut embedment analysis by optical coherence tomography |
| title_full_unstemmed |
Quantitative assessment of the stent/scaffold strut embedment analysis by optical coherence tomography |
| title_sort |
quantitative assessment of the stent/scaffold strut embedment analysis by optical coherence tomography |
| description |
The degree of stent/scaffold embedment could be a surrogate parameter of the vessel wall-stent/scaffold interaction and could have biological implications in the vascular response. We have developed a new specific software for the quantitative evaluation of embedment of struts by optical coherence tomography (OCT). In the present study, we described the algorithm of the embedment analysis and its reproducibility. The degree of embedment was evaluated as the ratio of the embedded part versus the whole strut height and subdivided into quartiles. The agreement and the inter- and intra-observer reproducibility were evaluated using the kappa and the interclass correlation coefficient (ICC). A total of 4 pullbacks of OCT images in 4 randomly selected coronary lesions with 3.0 × 18 mm devices [2 lesions with Absorb BVS and 2 lesions with XIENCE (both from Abbott Vascular, Santa Clara, CA, USA)] from Absorb Japan trial were evaluated by two investigators with QCU-CMS software version 4.69 (Leiden University Medical Center, Leiden, The Netherlands). Finally, 1481 polymeric struts in 174 cross-sections and 1415 metallic struts in 161 cross-sections were analyzed. Inter- and intra-observer reproducibility of quantitative measurements of embedment ratio and categorical assessment of embedment in Absorb BVS and XIENCE had excellent agreement with ICC ranging from 0.958 to 0.999 and kappa ranging from 0.850 to 0.980. The newly developed embedment software showed excellent reproducibility. Computer-assisted embedment analysis could be a feasible tool to assess the strut penetration into the vessel wall that could be a surrogate of acute injury caused by implantation of devices. |
| publisher |
Springer Netherlands |
| publishDate |
2016 |
| url |
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4879175/ |
| _version_ |
1613583775565873152 |